The Wizards are 4-0 when Porter starts this season.
The Wizards' bench has struggled defensively.
Wall's turnover with 28 seconds left sealed the Wizards' loss.
The Wizards face Trevor Ariza Monday for the first time since he left Washington for the Houston Rockets.
Pierce was a partial participant at practice Thursday after being sidelined Wednesday.
Flip Saunders returns to Verizon Center as Timberwolves head coach.
Neither player is expected to miss significant time.
Porter (hamstring) was inactive Saturday against the Bucks and Nene (foot) played just six minutes.
Porter dropped 19 of his 21 points in the second half after Paul Pierce's ejection.
Wall was held to 3-of-9 shooting and two assists in the second half.