By Joseph M. Lane, M.D. and Judith Andariese, R.N.
The huge bone factory we know as the human skeleton serves many wonderful and incredible functions. There's always something going on there, since bone is living tissue, constantly remodeling itself.
Some cells remove old bone (resorption), while others build new bone (formation). As we get older, bone loss outpaces bone formation. Some people lose bone mass more rapidly than others, for reasons that scientists don't yet fully understood.
Osteoporosis results when this decrease in bone mineral density is significant. It's a disease of global proportions, affecting more than 200 million people worldwideover 20 million women and 5 million men in the United States alone.
Who's at Risk?
Osteoporosiswhich literally means "porous bones"has been called the "silent" disease, because the loss of bone tissue progresses gradually (often without pain or symptoms) before a fracture occurs.
But fractures do occura million and a half each year, usually of the spine, hip or wrist. White and Asian women have twice as many fractures as African-American women. Hispanic women are also at significant risk.
Having risk factors doesn't mean you will develop the disease or have a fracture. ButÉif you have a number of the following characteristics, you should discuss testing your bone mineral levels with your doctor.
Major Risk Factors
- Smoking
- Low body weight (less than 127 lbs.)
- Corticosteroid medications/Chemotherapy
- Personal or family history of low-trauma fractures
Other Risk Factors
- Being female
- Early menopause
- Inadequate calcium intake
- Family history of osteoporosis
- Absence of menses (except for pregnancy)
- Excessive alcohol consumption
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