Roles That Proved to Be Heartbreaking

What really happened behind the scenes? The tabloids have lunged for every speck of evidence that Brad Pitt and Jennifer Aniston's relationship may have been undone by the pairing of Pitt with Angelina Jolie in the romance-action flick, "Mr. and Mrs. Smith," which opens this week. If the rumors are true, Brad and Jen's is far from the first coupling to be unraveled by a dalliance that began on the set. (It's not even the first credited to Ms. Jolie.) Some notable trailer-side trysts:

To Have and Have Not (1944)

The plot: The captain of a boat-for-hire grudgingly agrees to transport a French resistance fighter while wooing a sultry lounge singer.

The plot thickens: Humphrey Bogart had a legendary Hollywood love affair with co-star Lauren Bacall -- but first he had to dump his inconvenient third wife.

Stromboli (1950)

The plot: A young woman marries a fisherman in order to escape from a prison camp but finds life on his home island just as confining.

The plot thickens: Ingrid Bergman's husband, Peter Lindstrom, refused her a divorce (she eventually got one in Mexico) after she fell for director Roberto Rossellini and became pregnant. Bergman was drummed out of Hollywood and called "a powerful influence for evil" on Capitol Hill.

Porgy & Bess (1959)

The plot: The legendary Gershwin opera follows Bess, a woman with a bad reputation, as she tries to break free of her violent lover Crown. Only Porgy will take her in.

The plot thickens: Both Sidney Poitier and Diahann Carroll were wearing gold bands when they started their nine-year affair. His guilt, his 2000 autobiography said, was something "11 years of psychotherapy couldn't cure."

Splendor in the Grass (1961)

The plot: A young couple growing up in 1920s Kansas struggle with repressive mores.