Drugs With Special Side Effect Risks

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Tuesday, April 18, 2006

According to the Web site of Genelex, a DNA lab, the following common drugs are metabolized by enzymes in the cytochrome P450 family. This means that some people with certain genetic variations may be vulnerable to getting too much or too little of these drugs' active ingredients in their bloodstreams.

· CYP 2D6

Painkillers: codeine, OxyContin, Percocet, Ultram, Ultracet, Vicodin

Antidepressants: Effexor, Elavil, imipramine, Paxil, Prozac

Antipsychotics: Haldol, Risperdal

Cardiovascular: Coreg, Inderal, Lopressor, Timoptic, Toprol

ADHD treatment: Adderal, Concerta, Strattera

Miscellaneous: Claritin, dextromethorphan (active ingredient in most cough suppressants), Flomax

· CYP 2C19

Painkillers: methadone


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