Senators Denounce Scientist's Stem Cell Claims

Sen. Arlen Specter:
Sen. Arlen Specter: "It's a big black eye if scientists are making false and inaccurate representations." (Alex Wong - Getty Images)
By Rick Weiss
Washington Post Staff Writer
Thursday, September 7, 2006

Two senators who strongly support human embryonic stem cell research lashed out yesterday at the scientist who recently reported the creation of those cells by a method that does not require the destruction of embryos, saying the scientist and his company have harmed the struggling field by overstating their results.

"It's a big black eye if scientists are making false and inaccurate representations," a combative Sen. Arlen Specter (R-Pa.) said during a hearing of the Senate Appropriations labor, health and human services subcommittee, which he chairs.

Robert Lanza of Advanced Cell Technology (ACT) in Worcester, Mass., defended his work and the company's statements. "Our paper is 100 percent correct," said the visibly shaken scientist, referring to the highly publicized article that appeared in the Aug. 24 issue of the journal Nature.

"You're on the ropes!" Specter retorted, capping one of several exchanges in which he and Sen. Tom Harkin (D-Iowa), a fellow advocate of stem cell research, repeatedly interrupted and scolded Lanza.

At issue was the initial publicity and resulting media coverage of ACT's widely reported experiment, which showed that a single cell taken from a human embryo can be coaxed to become a colony of stem cells.

Embryonic stem cells are prized for their medical and research potential, and until Lanza's experiment they had been grown only by methods that necessitated the destruction of an embryo.

Because the removal of a single cell from an early embryo is widely regarded as harmless (hundreds of apparently healthy children began as fertility clinic embryos that first had a cell or two removed for testing purposes), ACT characterized the technique as a way to make stem cells without destroying embryos.

But opponents of the research, most prominently representatives of the Roman Catholic Church, quickly attacked that claim as bordering on fraudulent. They noted that, in ACT's experiments, the scientists destroyed the embryos to get as many single cells as possible to work with.

While that fact was clear in the Nature report, it was less than clear to some members of the media and the public.

Specter and Harkin focused on what they said was the main reason for the confusion: the company's news release, which said the team had derived stem cells "using an approach that does not harm embryos."

The approach -- removing single cells -- may be harmless when only one cell is removed, the senators agreed. But in this case, it did harm embryos because the scientists, wanting to make the most of the few embryos donated for the work, took many cells from each.

Similarly, the release quoted Lanza as saying: "We have demonstrated, for the first time, that human embryonic stem cells can be generated without interfering with the embryo's potential for life."

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