An Affair Of the Head

Actually they weren't, and neither are you, not really, when you fall passionately in love.

In her most recent research, Fisher and colleagues gave 32 love-struck subjects an MRI scan while they viewed a picture of their beloved.

Boy, did their brains light up!

There are two shrimp-size things on either side of your brain called the caudate nuclei. This is the gear that operates bodily movements and the body's reward system: "the mind's network for general arousal, sensations of pleasure, and the motivation to acquire rewards," Fisher writes. And when the test subjects looked at their sweeties, these things started singing "Loosen Up My Buttons" with the Pussycat Dolls!

This, then, kicked the party over to the tiny ventral tegmental area, a little peapod-size thingy that sends dopamine bopping around your head.

This is what scientists call lots of fun.

A separate study by Italian researchers several years ago showed something else.

Serotonin, another neurotransmitter in the brain associated with obsession, depression and racing thoughts, was greatly affected -- right down to the molecular level -- by romance and surging dopamine. People newly in love and people with obsessive-compulsive disorder showed the same lowered levels of the "platelet 5-HT transporter." In other words, dopamine appears to suppress serotonin, which in turn triggers obsessive-compulsive thought patterns.

You can't stop thinking about Dave. No wonder! Dave's hiding under a wet flap of cortex!

Your brain is officially in love, and it officially is driving you crazy.

Oliver Sacks, the famed neurologist and author, once cited the case of a 90-year-old woman who had suddenly become radiant, flirty, even frisky. The diagnosis: a long-delayed onset of neurosyphilis had loosed the reins on her inhibitions.

She did not want to be treated.