Vaccine Could One Day Control High Blood Pressure

One expert thinks this finding could be a breakthrough in helping patients control their blood pressure.

"Poorly controlled blood pressure remains a worldwide health-care problem and contributes greatly to heart attacks, strokes, and cardiovascular deaths," said Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles.

Although there are lifestyle modifications and a number of effective and reasonably well-tolerated medications that can help control blood pressure, many patients don't adhere to their regimens in a way that works effectively, Fonarow said. "A vaccinate for controlling blood pressure, if proven to be safe and effective, could represent an important therapeutic advance," he said.

This study is the first to show promising data with a vaccine against angiotensin II, a potent constrictor of blood vessels, in patients with mild to moderate hypertension, Fonarow said.

"While further studies for safety and efficacy, including ones that are larger and follow patients longer, are clearly necessary, this is an exciting development in the search for new and more effective means to help patients achieve and maintain control of high blood pressure," he said.

More information

To learn more about high blood pressure, visit the American Heart Association.

SOURCES: Martin Bachmann, Ph.D., Cytos Biotechnology, Schlieren, Switzerland; Gregg C. Fonarow, M.D., professor, cardiology, University of California, Los Angeles; March 8, 2008,The Lancet