Kennedy Faced Brain Surgeon's Knife While Awake

TUESDAY, June 3 (HealthDay News) -- Sen. Edward Kennedy certainly was heroic as he underwent surgery Monday for a malignant brain tumor whilepartially awake. But he was no more a superhero than other men and women who suffer from the same condition and are faced with the same type of procedure to remove their cancer.

Experts say this type of brain surgery, when the patient is conscious for at least part of the operation, is not uncommon.

"It's specialized for tumor surgeons, but it's highly warranted in this type of tumor and would be considered the standard of care," said Dr. John S. Yu, director of surgical neuro-oncology at Cedars-Sinai Medical Center in Los Angeles.

"When the tumor is very close to very critical brain areas, such as language or movement, a lot of surgeons will choose to do this procedure aware," added Dr. Walter Jean, associate professor of neurosurgery at Georgetown University Hospital, in Washington, D.C. "You have to have a big enough center that the surgeon is comfortable with this. Certain centers do it more than others."

And incredibly strange as it may seem, keeping patients awake -- or at least partially awake for part of the procedure -- is critical, so crucial brain functions aren't destroyed.

Equally strange, the actual brain does not have the ability to feel.

"The brain itself is not sensitive to touch," said Dr. Eugene S. Flamm, professor and chairman of the department of neurosurgery at Montefiore Medical Center and Albert Einstein College of Medicine in New York City. "It controls all our sensation. You can manipulate the brain and do what you have to do in the brain without the patient being aware of it."

But the patient isn't awake throughout the whole surgical procedure and certainly not while the scalp and skull are being opened or closed -- these areascanfeel pain, as anyone who has hit their head on a sharp edge can attest.

"The only painful part of the procedure is when you enter the skin and bone, so the patient is asleep," Yu confirmed.

Patients are awakened from their sedated state, at least somewhat, while the surgeons determine which parts of the tumor can be safely removed without damaging vital nerve centers that control functions such as speech, cognition and movement. During this phase, the patient's head is completely immobilized in a rigid frame, while the rest of the body just lays on a gurney, Yu said.

During this awake period (lasting perhaps 30 to 40 minutes, according to Yu), doctors essentially "map" the brain, stimulating different areas with electronic probes to see how the patient responds. Each person's brain is structured a bit differently, so what works for one patient may not work for the next.

The parietal lobe of the brain, where Sen. Kennedy's tumor was located, is involved with speech, so that appears to have been the main concern of his team of specialists. But the front part of the parietal area also abuts the sensory cortex, which is connected to motor function, Yu explained.