Things don't work out so well with Sheldon and Amy on "The Big Bang Theory" (CBS at 8), but Sheldon's friends get more frightened than ever when he decides to quit seeking affection from people and look for an alternative to human companionship.
"Jersey Shore" has already given us so much, but there's yet another situation thanks to the MTV reality show: Booth and Brennan head to the shore for a Jersey-themed episode on "Bones" (Fox at 8), involving a decomposing body found in a popular nightclub.
When a congresswoman (guest star Queen Latifah) reviewing the NBC-Kabletown merger demands that NBC have more diverse programming on "30 Rock" (NBC at 8:30), Jack goes to Tracy for help -- even though Tracy's generally the last person anyone would go to for ideas based in reality.
Drumroll, please . . . the much-anticipated topic from "The Real Housewives of D.C." (Bravo at 9) airs Thursday night in the Season 1 finale, which looks at the aftermath of Tareq and Michaele Salahi's attendance at the White House state dinner last November. DVR alert: The episode will last for an hour and 15 minutes; at 10:15, the Salahis sit down with Bravo's Andy Cohen on "Watch What Happens: Live" to discuss the episode.
With people discussing the merits of a Facebook movie after seeing the recently opened "The Social Network," Bloomberg TV (Channel 103 on Comcast) features Facebook founder Mark Zuckerberg on "Bloomberg Game Changers" (at 9); the show also has interviews with Zuckerberg's Harvard classmates Cameron and Tyler Winklevoss and Divya Narendra, who claimed Zuckerberg stole their idea for the site.
A vampire and werewolf fan convention meets a grisly end when someone is murdered on "CSI" (CBS at 9), and the team descends upon the scene to investigate.
Derek deals with family drama when his estranged sister shows up at the hospital on "Grey's Anatomy" (ABC at 9), and in between, he helps Meredith try to get Cristina back into her work routine after she suffers post-traumatic stress.
New series "Kick Off Cook Off" (TLC at 10, 10:30), hosted by ESPN's Erin Andrews, challenges two teams to come up with the best tailgate recipes to win a cash prize -- and in a fun twist, the die-hard football fans don't realize they're also competing against football players.
Comedian and talk show host Stephen Colbert is a guest on "Late Show With David Letterman" (CBS at 11:35), along with actor Johnny Knoxville and musical guests Gorillaz.
"The Tonight Show With Jay Leno" (NBC at 11:35) hosts actress Katherine Heigl, "Outsourced" actor Ben Rappaport and a performance by Meat Loaf.
-- Emily Yahr