Dylan McDermott, Josh Malina and Michael Vartan star as friends at the top of their game -- at least until the women in their lives enter the room.

"Sex and the City" creator Darren Star takes four women back to Manhattan in this new dramedy.

A new sitcom follows four guys as they commiserate about life and work on their daily commute.

Inspired by the GEICO commercials, ABC launches a sitcom centered on cavemen in modern-day America.

Peter Krause plays a lawyer lured to help the wealthy Darling family.

The much-anticipated "Grey's Anatomy" spin-off follows the travails of Dr. Addison Shepherd in L.A.

A 'forensic fairytale' about a guy who is able to touch dead things and bring them back to life.

Christina Applegate is a woman who wakes up from amnesia to learn there wasn't much to like in the person she once was.

Based on characters created by novelist James Patterson, four working women in San Francisco solve murder cases.

From the creator of "Two and a Half Men," comes a sitcom about two geeks who befriend their beautiful neighbor.

A drama focuses on the Cuban-American Duque family and their efforts to control their rum and sugar empire. Jimmy Smits leads a cast that includes Rita Moreno, Hector Elizondo and Nestor Carbonell.

A reality series gives 40 kids 40 days to work together -- with no adults -- and turn a deserted former mining town into their own new world.

Vampire detective Mick St. John solves crimes as he struggles with the undead and his love for a mortal woman.

Based on the BBC series "Viva Blackpool," the hour long drama-musical-thriller centers on one man's efforts to open a casino in Laughlin, Nev. Executive producer Hugh Jackman has a recurring guest role.

A sitcom centers on the madcap of a perpetual High School geek and the Pakistani exchange student that comes to live with his family.

After learning his parents sold his soul to the devil before he was born, a young man begins work as Satan's bounty hunter, capturing souls that have escaped eternal damnation.

From Josh Schwartz, the creator of "The O.C." comes a drama about the trials of privileged prep schoolers on Manhattan's Upper East Side.

The drama follows a veterinarian and his family as they start a new life on a wildlife game reserve in South Africa.

Sitcom veterans Kelsey Grammer and Patricia Heaton play ex-lovers reunited on-air as TV news anchors in Pittsburgh in a new half-hour comedy.

Julianna Margulies heads a team of defense lawyers taking on risky and unpopular cases. Dennis Leary serves as executive producer.

Anthony Anderson leads a group of cops striving to enforce the law in post-Hurricane Katrina New Orleans.

A New York City homicide detective solves cases as he struggles with his own immortality.

From "Gilmore Girls" creator Amy Sherman-Palladino comes a new comedy about two very different sisters played by Parker Posey and Lauren Ambrose.

From the Farrelly brothers comedy team comes a comedy centered on two newly divorced best friends and their attempts to re-enter the dating pool.

Jaime Sommers is reborn in the NBC action drama that brings the 70's TV icon into the 21st century.

Chuck Bartowski is a computer geek by day and government operative at night.

A new drama centers on a newspaper reporter as he travels through time and the conflicts that arise between his past and present.

A detective returns to the force after years in prison for a crime he never comitted.