Deborah Pryce was elected to two terms as a Franklin County Municipal Court judge in 1985 and 1991. She was elected to the U.S. House in 1992 with 44 percent of the vote, defeating Democrat Richard Cordray and independent Linda Reidelbach. She was re-elected in 1994 with 68 percent, defeating Democrat Bill Buckel.
In 1996, she was re-elected with 71 percent of the vote, defeating Democrat Clifford Arnebeck. Pryce was re-elected in 1998, defeating Democrat Adam Miller and independent candidate Kevin Nestor with 59 percent of the vote. She was re-elected with 68 percent of the vote in 2000, defeating Bill Buckel.
In 2002, Pryce beat Democrat Mark P. Brown 67 percent to 33 percent. Pryce had 84 percent of the vote to win the March 2, 2004, primary for the 15th District.