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    Complications & Conditions of Allergic Sensitivity

  • Anaphylaxis
  • Asthma
  • Ear Infections
  • Eczema
  • Nasal Polyps
  • Sinusitis
  • Hives

    As if allergy symptoms weren't enough, some allergic people also develop one or more associated medical problems – including nasal polyps, sinusitis, ear infections, eczema and asthma. Sometimes a complication results from the allergy itself. For instance, some people with allergies have frequent headaches, usually the result of sinus congestion caused by inhaling allergens. Some of the more common complications include:

    Anaphylaxis
    The most dangerous allergy syndrome is anaphylaxis, a sudden and potentially deadly reaction. Luckily, it's also one of the most infrequent, although it claims several hundred lives each year.

    Anaphylaxis occurs when your immune system goes wild against an allergen, resulting in the most intense allergic reaction. Mild cases can cause severe itching or localized hives, but severe cases can trigger a swollen throat and a constriction of the airways, rapid pulse, loss of consciousness, a sudden drop in blood pressure (shock), weakness, cardiac collapse and other symptoms that require immediate medical treatment – specifically, a shot of adrenaline (epinephrine) to open the airway and reduce swelling. Cardiovascular resuscitation and emergency tracheotomy sometimes must also be performed.

    Anaphylaxis can occur within seconds and a variety of allergens can cause it. Usually, it results from allergic reactions to insect venoms; vaccinations, medications and some medical tests; or foods like peanuts and shellfish. Those who have experienced anaphylaxis in the past are advised to carry a portable emergency kit with an epinephrine injection, especially when exposure to the allergen (like an insect venom) is likely. However, these injections are not designed to replace emergency hospital treatment; rather, they should control symptoms until you get to the hospital.

    Asthma
    Allergies are involved in many cases of asthma (especially in children), a condition characterized by an abnormal response of the lower airways to a wide variety of allergic and non-allergic substances.

    Ear Infections
    Children with hay fever and other forms of allergic rhinitis may also be plagued by chronic ear infections. Sometimes, these infections can lead to hearing loss or delayed speech development. The problem results from an obstruction in the passages between the middle ear and the nose. Symptoms include pain, pressure or a "bubbling sensation" in the ear.

    Eczema
    Allergies can also lead to eczema, also called atopic dermatitis. This condition causes itching and a red rash, usually on the cheeks, but the neck, arms and legs may also be affected (particularly the backs of the elbows and knees and the area behind the ears). In severe cases, "sheets" of thick, purplish rash spread across the body. Scratching the itch spreads the rash and may lead to oozing and formation of a crust. Eczema is most common in children with a family history of allergy, and affected children are more likely than others to develop hay fever and asthma. Children allergic to eggs, milk, peanuts, soy, wheat or fish are most likely to have eczema. Even when an allergy is not apparent, children with eczema often have high levels of IgE, the allergy antibody.

    Eczema is treated with corticosteroid creams and ointments and, if needed, antihistamines to control itching. In addition, the following measures may be helpful:

    • Try to avoid exposing your skin to sudden and extreme changes in air temperature.
    • Wear soft, light-weight clothing. Tight clothing made from rough, scratchy material is too irritating to the skin.
    • When washing, avoid soap and hot water; both can draw natural oil from the skin and dry it further. Instead, bathe in lukewarm water with a moisturizing "cleansing" bar or liquid "non-irritating" cleanser; both are available at most drugstores. And remember: Don't rub your skin with a towel; pat yourself dry. Apply moisturizers when you have finished bathing.

    Nasal Polyps
    These grape-like clusters of swollen tissue that hang in the nasal passages can result from the inflamed sinuses that develop from allergies. Nasal polyps can make your nose feel blocked and full and may affect your sense of smell. When total nasal obstruction occurs, they're treated with the drug prednisone, which shrinks the inflamed tissues. Afterward, you may need to use a steroid nasal spray regularly to prevent polyps from growing. If this treatment doesn't help, the polyps can be removed surgically – a procedure known as polypectomy – although they may recur. Polypectomy is performed by an otolaryngologist, a physician who specializes in the treatment of ear, nose and throat disorders.

    Sinusitis
    Allergies that affect the nose can lead to sinusitis, an inflammation of the sinuses, the air spaces in the bone surrounding the nose. Nasal obstruction due to allergies can either trap air in the sinuses or prevent it from reaching the sinuses, causing intense pain; you may also get sinus headaches when you wake up in the morning. The site of the pain and/or headache depends on which sinuses are affected:

    • If the maxillary sinuses inside your cheekbones are infected, the pain will be in your upper jaw and teeth, and your cheeks may be tender.
    • If your ethmoid sinuses behind the bridge of the nose are infected, the pain will be around your eyes. Your eyelids may be swollen and you may have tenderness on the sides of your nose, a stuffy nose and a temporary loss of your sense of smell.
    • When the sphenoid sinuses above the ethmoids are infected, you'll probably have an earache, neck pain, and an ache on the top of the head.

    In addition to pain, sinusitis also can cause postnasal drip due to the drainage of mucus from the nose into the throat.

    Hives
    Hives (urticaria) are raised, red, itchy areas on the skin (also called wheals or welts) that appear as an allergic skin reaction. There can be one or many hives that vary in size and shape.

    Most often, no cause for hives can be identified. Clusters of hives may appear as an allergic reaction to one or more factors (irritants) such as foods, medications, insect bites or stings, infections, or emotional stress.

    Histamine, a body chemical, is released in response to the irritant that causes the hives to form. These hives or wheals may appear on any part of the body, but are most common on the arms, legs, and trunk. The rash may last for a few minutes or several days. It may recur and can be uncomfortable.

    In the case of a severe reaction to a bee sting, for example, your face and throat may swell. Hives may rarely cause problems with breathing, creating the danger of suffocation.

    Your doctor will examine the affected area and will ask about your history of sensitivity to such things as:

    • drugs (such as penicillin, aspirin, or sulfa)
    • plants (such as nettles) and pollens
    • animal fur
    • insect bites or stings
    • exposure to heat, cold, or sunshine.

    To determine the cause of your hives, the doctor may suggest that you do the following:

    • Keep a detailed diary of everything you eat, drink, take, or are exposed to for 2 to 4 weeks.
    • Avoid foods, one at a time, to which you think you may be allergic.
    • See an allergist for skin tests.

    It is easiest to identify drugs, foods, or plants that may cause you to have hives because the response usually occurs within an hour of exposure. Finding what triggers hives such as emotional stress or multiple allergies may take more time and require skin or other tests.

    The treatment your doctor recommends will depend on how serious your hives are. He or she may suggest that you do one or more of the following to relieve the itching and reduce the swelling:

    • Soak in a lukewarm bath or use cool compresses.
    • Avoid heat or rubbing, which releases more histamines.
    • Take antihistamine medicine to reduce the allergic response.

    If the rash is severe and/or not responding to the above treatments, you may need to take a brief course of oral corticosteroids (for example, prednisone).

    Some allergic reactions are emergencies. If your hives have abrupt onset and are spreading quickly, you will likely receive an injection of antihistamine such as Benadryl (diphenhydramine). If there is any question of throat swelling or tightness or of difficult breathing or of wheezing, you will also receive an injection of epinephrine (adrenaline) to counteract the reaction. Once the emergency symptoms have been treated you will be instructed in medication to take for the next several hours to days to prevent the reaction from recurring.

    These severe allergic reactions can be life-threatening and require immediate medical treatment.

    The effects of hives can last from a few hours to several weeks or months. Hives will eventually clear without treatment, but taking drugs such as antihistamines or corticosteroids help the hives go away faster, treat the itch, and prevent new hive formation.

    Chronic urticaria last for a longer period. Most often, more than 50% of the time, it is not possible to determine their cause. Antihistamines are usually very helpful. The hives resolve spontaneously after weeks or months but may recur off and on.

    Call the doctor or 911 at once if you have an allergic response that affects your breathing.

    In addition, follow these guidelines:

    • If your face begins to swell around the eyes and lips, call your doctor or 911 at once.
    • Take antihistamines or other medications to help relieve your symptoms. Be sure to ask your doctor or pharmacist about possible side effects or drug interactions.
    • Avoid foods that seem to cause you to break out.

    If you have a known severe allergy, such as to a bee sting or a food such as peanuts, which you might inadvertently contact, ask your doctor about carrying EpipenŽ. Epipen is a single dose injection kit of epinephrine you can give yourself to counteract the allergic reaction until help arrives.

    When you know the cause of your hives you should take steps to avoid the offending irritant. You may need to take frequent, even daily, antihistamine to prevent recurrences.

    Last updated December 03, 1996

    1996-1999 The Johns Hopkins University. All rights reserved. Source: Inteli-Health Inc. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. You should seek prompt medical care for any specific health issues and consult your physician before starting a fitness regimen. Use of this online service is subject to InteliHealth's disclaimer and the terms and conditions.

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