Baltimore Federal Savings & Loan Association, Maryland's second largest S&L, has reported a 43 percent drop in profits for the first quarter of 1980.

Baltimore Federal, with assets of more than $1 billion, reported first-quarter profits of $801,910, down from profits of $1.4 million for the first quarter last year. Per-share figures weren't given.

Savings deposits increased by $14.1 million during the quarter compared with a $22.6 million increase in deposits for the same quarter in 1979. Baltimore Federal's assets at the end of the quarter were $1.04 billion, up about 6 percent during the preceding 12 months.

In another report, D.C. National Bank reported net profits of $362,660 ($1.77 a share).First-quarter 1979 per-share profits were $1.38.

Madison National Bank of Washington reported after-tax profits of $548,104 ($1.42 a share) for the first quarter of 1980, up 29 percent from $423,939 ($1.10) during the first quarter of 1979.

Total assets at Madison National increased by 23 percent to $162 million from $131 million at the end of last year's first quarter. Deposits rose to $134 million, an increase of 16 percent over deposits on March 31, 1979.

Coldwell Banker & Co., which owns Routh Robbins real estate in the metropolitan area, reported fiscal third-quarter profits of $2.08 million (50 cents a share) up from $1.85 million (43 cents). Nine-month profits for Coldwell Banker were $9 million, up from $7.5 million reported for the same nine months last year.