In the laboratory of business, the entrepreneur is the chief chemist.

And good business chemistry is the goal at the Entrepreneurship Institute's Second D.C. Area Forum to be held Friday and Saturday at the Shoreham Hotel.

Sponsored by the Entrepreneurship Institute of Columbus, Ohio, a nonprofit international organization that conducts forums throughout the country, the two-day event will feature lectures, workshops and one-on-one discussions with area entrepreneurs and business advisers on launching and managing a successful enterprise.

A $195 entrance fee (more for late registrants) will secure access to more than 50 business professionals, accountants, attorneys, bankers and venture capitalists.

Addressing the forum will be John Hechinger, president of the Hechinger Co.; John Koons Jr., president of J.K.J. Chevrolet; and Oliver T. Carr, president of Oliver T. Carr Co.

After a morning lecture, participants will divide into small groups for workshops on subjects from business planning to taxes. Later, there will be a chance for those attending to discuss their specific situation with a panelist.

Forum participants will have an opportunity to make business contacts and to listen to colleagues discuss their successes -- and failures.

With the name recognition of the executives scheduled to appear, the forum's organizers hope to repeat the response they received last February when their program sold out six days after registration opened.

For the second forum, the institute has the support of the D.C. Department of Employment Services and the D.C. Office of Economic Development.

Among the forum's business sponsors are Riggs National Bank; D.C. National Bank; Peat, Marwick and Mitchell, and Safeway Stores Inc.

Anyone interested in registering can phone the Entrepreneurship Institute at (202) 371-0001.