The Communications Satellite Corp.'s government services division has signed an agreement with Computer Science Corp. (CSC) to bid for a State Department communications contract that may be worth more than $200 million.

The contract is to design and operate the global Department of State Telecommunications Network (DOSTN) connecting 275 domestic and foreign locations of the State Department and other U.S. foreign affairs agencies with a distributive computer network.

The State Department now has a network in which all circuits reach the State Department through a series of point-to-point connections. The current system is managed through these separate connections, but the new system will be managed from one central location. DOSTN "offers more flexibility than the present system," said Chuck Wafle, director of federal programs for Comsat. "It can diagnose problems and reconfigure the network from a single point."

Talks about a teaming agreement started about eight months ago, according to Walter J. Culver, president of CSC's systems division. "We chose Comsat because it knows government requirements and has expertise in international satellite communications."

"Actually, I think I made the first phone call," said Wafle. "Comsat was thinking of the prime role but after looking at the risk, we decided a subcontractor role would be better. So, we made a short list of the companies likely to win the contract and went after them."

Comsat is designing the satellite system, setting up ground stations in the United States and coordinating its satellites with foreign post, telephone and telegraph systems.

CSC is responsible for designing and installing the system, providing the software and hardware, and documenting the system.

"This is a complex contract," said Culver. "The State Department wants prices for 11 years, state-of-the-art security, mixed voice, data and TV transmissions. We had to start preparing one year before the request proposal."

The State Department's request proposal is expected in November or December of this year. The project must be approved by Congress before the contract is awarded.

"CSC and Comsat may design a lab version of the system before the request proposal date," said Culver. "And we may actually start building DOSTN before the contract winner is announced, to work out the bugs.

"It is a risk. By the time the contract is awarded, Comsat and CSC will have invested about $2 million in the project. I expect two or three major companies to be bidding against us.

"But this is a risky business. A company has to be big enough to absorb the losses," said Culver. Both CSC, with 1986 revenue of $838.6 million, and Comsat, with 1986 revenue of $466.3 million, fit that bill.

Right now, CSC's systems division is looking at five contracts,similar to DOTSN, that will all be awarded government services division is bidding on at least two other contracts.

After two years and $2 million invested in this State Department contract, "we will cry a lot if we lose," said Culver.

The U.S. Trade and Patent Office issued a patent to Interleukin-2 Inc. of Alexandria for a process to produce an interleukin-1 preparation.

Interleukin-1 is known as a wound hormone that helps repair injured tissue. It is prepared from normal blood cells that have been treated to remove blood serum proteins. The treated cells are stimulated with a mitogen and then incubated in a serum-free tissue culture medium where interleukin-1 is given off by the cells and collected.

Interleukin-1 is being tested for use in treating rheumatoid arthritis, multiple sclerosis and burns and as a protective agent against large doses of radiation therapy.

Interleukin-2 Inc., founded in 1983, is best known for producing a cell-cultured interleukin-2 that is identical to the substance produced by the human immune system.

The substance is still being tested, but so far has proven successful in treating some forms of cancer with fewer side effects than recombinant interleukin-2.

Atlantic Research Corp. and its joint venture partner, Hercules Inc., have been awarded a $22.3 million, five-year contract by the Air Force to develop a ramjet engine for air-to-air missile systems.

Ramjet engines operate without a rotating parts such as compressors or turbines. A rocket gets the engine up to speed and fuel injections sustain its speed. is the simple design, which saves manufacturing and operating costs," said Ruben Canney, marketing manager for Atlantic Research. "The engine can be stored for a long time without maintainence."

Under the contract, ARC and Hercules will test the new engine's effectiveness in ground tests only.

Three Score of Tucker, Ga., will soon become a subsidiary of Cadmus Communications Corp. in Richmond under an agreement reached last month. Cadmus is not releasing the terms of the purchase but the company says it involved both cash and stock.

Three Score designs and prints catalogues for major department stores, such as Rich's, Macy's in Atlanta, Marshall Field and Jordan Marsh.

The company's sales are expected to exceed $14.5 million by Aug. 31, the end of its fiscal year.

"Three Score's market niche in creating specialty retail catalogs will complement and extend our direct marketing and promotional printing markets," said Wallace Stettinius, Cadmus chairman and chief executive officers.

and retain its current management, according to Clarence Swearngan Jr., communications specialist for Cadmus.