The agreement to let China join the World Trade Organization lit fireworks under the stock of U.S. China Industrial Exchange, a Bethesda company that runs a hospital in Beijing and exports medical equipment to China for U.S. manufacturers.

Shares of the the company jumped from $16 a share on Monday to a few cents shy of $26 on Wednesday and closed Friday at $25.25.

"We have a very strong and bullish view of the potential for the Chinese market," said Lawrence Pemble, the chief financial officer. "As WTO agreements are implemented over the next several years, we think the potential for China as an American marketplace will continue to grow."

The revenue of the company, known as Chindex, jumped to $13.2 million from $5.5 million in the three months ended June 30. The company also posted a profit of $817,000 ($1.03 a share), compared with a loss of $671,000 a year earlier.

The Washington Post-Bloomberg regional stock index climbed for the sixth consecutive week to close at 175.09, up 1.5 percent. It ended the week 2.1 percent below its July 16 high of 178.82.

Other big gainers for the week included Credit Management Solutions Inc. of Annapolis Junction, which signed a contract to provide its automatic car loan approval and processing system to a DaimlerChrisler AG subsidiary.

Shares of Netrix Corp. of Herndon were driven up after Sonic Telcom, a privately owned communications company just down the road, agreed to use Netrix products to carry phone calls on its data network.

On the downside, shares of U.S. Office Products Co. headed back toward their all-time low after the company posted shrinking sales and exploding losses. Revenue for the three months ended Oct. 23 fell to $642.5 million from $677.2 million a year earlier and the loss burgeoned to $29.6 million from $4 million.

U.S. Office Products' stock bottomed out at $2.531 1/4 a couple of weeks ago, then recovered to more than $4, only to fall again after the earnings report was released.

The week's top loser was Dynex Capital Inc., a Richmond mobile-home-financing company. Its stock fell after the company sold part of its business to GE Capital Corp.