Digene's report of increased sales of its flagship diagnostic test, which mitigated news of a bigger second-quarter loss, helped the Gaithersburg-based biotech firm emerge as the leading local gainer.

Digene lost $1.3 million (7 cents per share) in the three months ended Dec. 31, up from $1.1 million (6 cents) in the year-ago quarter. The company's revenue, however, rose to $14.5 million from $11.6 million, as sales of its diagnostic products for human papillomavirus grew.

The company also said it expects its HPV test to receive approval as a primary means of detection for cervical cancer by the end of next month. The test is used as a follow-up test to Pap smears.

Shares of Digene rose 33 percent last week to close at $15.29.

The Washington Post-Bloomberg regional stock index fell 2.58 points to close at 157.14. The NVTC Potomac Tech 60, which tracks 60 local technology companies, closed at 524.24, down 13.74 points.

Increased revenue also pushed shares of Advisory Board to close significantly higher last week.

The Washington health-care information and management firm's revenue rose to $25.9 million from $20.7 million for the three months ended Dec. 31. The company's third-quarter income fell to $3.3 million (19 cents), compared with $4.7 million (28 cents) in the year-ago quarter. Shares of Advisory Board closed at $33.51 Friday, up 15 percent for the week.

VSE, an Alexandria engineering and security services firm, said last week it led a 29-member team that was awarded a contract with the Army potentially worth a total of $2.9 million over eight years if all the options are exercised.

Under the contract, VSE is to provide equipment and services to the Army Communications-Electronics Command at Fort Monmouth, N.J. VSE shares rose 14 percent to close at $12.55 last week.

Atlantic Coast Airlines said traffic rose 27.9 percent in January, compared with the same quarter of the previous year, but shares of its parent company, Atlantic Coast Airline Holdings, were among the leading local decliners for the second straight week.

After falling 21 percent the previous week, shares of the Dulles airline dropped 19 percent last week to close at $8.09.

Investors balked when Circuit City Stores said it would cut about 2,000 jobs and do away with commission-based pay last week. The Richmond electronics retailer said it is implementing the changes to boost its bottom line.

The company's stock fell 19 percent last week to close at $4.87 a share.