Local girl makes good and marries well. That's one way to look at it. Friends in Washington have learned that, after a brief courtship, 27-year-old model Betsy Farley has married Khalid Khashoggi, the 21-year-old son of Adnan Khashoggi, one of the richest men in the world. Farley, the daughter of Edwin and Inez Minetree of Prospect Hill, Va., near Warrenton, had dated a few other famous men before deciding to settle down, including actor Sylvester Stallone and Stefano Casiraghi, now the husband of Princess Caroline of Monaco.

Farley, whose face has been on a Washingtonian magazine cover and who has modeled in Europe, met the young Khashoggi, a Princeton student, at a New Year's Eve party on his father's yacht off the coast of Spain. The couple flew from Spain to Kenya to go on a safari and were married there Jan. 26. It is Farley's second marriage, Khashoggi's first. The couple is honeymooning in Spain and will be going on to London before coming back to the United States in about three weeks. It all happened so fast that Farley's parents haven't yet met their new son-in-law. Things zip along that way in the jet stream. Califano & the Cigarette Crusade

The no-smoking campaign that former Health, Education and Welfare secretary Joseph Califano is conducting at the law firm of Dewey, Ballantine has attracted the attention of Surgeon General C. Everett Koop. The law firm at 1775 Pennsylvania Ave., where Califano works, has set a goal of being smoking-free by Oct. 1, and given half the encouragement, Califano will go for a smoking-free building, something that would be unique and precedent-setting.

After reading about Califano's assault on the deadly cigarette, Koop wrote Califano that he was "delighted you had the vision and the courage to take this stand." Stopping smoking at the work site, he wrote, encourages the smoker to quit and, more importantly, addresses the problem of "side-stream" smoking. Koop pointed out that when a nonsmoker and smoker work together in the average-sized office, the two-pack-a-day smoker forces the nonsmoking companion to "smoke" three cigarettes a day, "which is without question a health hazard."

Califano also had a call from a woman whose husband had died of lung cancer at 46 and who herself had lost a lung to smoking. She said she would be happy to talk to anyone who was trying to quit. Who knows? Just like nuclear-free zones, there could be a time of smoke-free zones. End Notes

Getting married on Christmas Eve and working on New Year's Eve made it difficult for Peter Duchin's friends to toast him and his new wife Brooke Hayward. Rose Narva had a belated wedding celebration for Duchin and Hayward last night at the Jefferson Hotel. The guests included James and Sylvia Symington, Clayton and Holly Fritchey, Vernon Jordan, Frank Mankiewicz, Joe Alsop and Richard Holbrooke . . .

Former vice president Walter Mondale and Joan Mondale are going to be out late Friday night attending the midnight show at the Source Warehouse Rep. They have a good reason: Their 23-year-old son William will be appearing as one of the Joker's henchmen in "Batman vs. the League of Doom." The show will run over the next six weekends, and young Mondale says several of his former Brown University theater classmates are involved with the production . . .

March is going to be busy for Tip O'Neill, Washington's favorite Irish-American. On St. Patrick's Day there will be the big dinner in his honor to mark his 50 years in politics. On March 12, the speaker of the house is being honored at a Capitol Hill cocktail party where he will receive the satin orange, green and white sash signifying that he will be Grand Marshal of the St. Patrick's Day parade here on March 16, in which the band from his alma mater Boston College also will be marching . . .

Temple University has invited freed Soviet dissident Anatoly Scharansky to receive an honorary degree that the school's board of trustees voted for him in April 1984 . . .

Stanford University now is not going to get either Soviet leader Mikhail Gorbachev or comedian Bill Cosby as a commencement speaker. Both have other commitments on June 15. The next person to be asked is "Nightline" anchor Ted Koppel. If he's not available, someone probably will be, but it's going to get embarrassing after a while . . .

The Washington Capitals have been having an exceptional season and veteran Washington sportswriter/broadcaster Mo Siegel was asked if he wanted to go to one of the sold-out games. To which Siegel replied with a wry grin, "I ain't been to a hockey game since Pele retired" . . .