Alcohol consumption on an airplane will have twice the effect that it does at sea level.

So reports Mayovox, a Mayo Clinic publication, as part of advice to air travelers who want to avoid physical discomforts -- deyhydration, dry skin, pressure changes, motion sickness and anxiety -- when flying.

Among the advice:

Drink as much as a glass of water an hour to counteract an aircraft's low humidity.

Avoid excess use of alcohol or coffee (or other caffeine-containing beverages: tea and colas), all of which cause fluid depletion.

Avoid smoking, which dries out sinuses and diminishes oxygen intake.

To combat swelling of ankles or feet, abdominal bloating and ear discomfort:

Avoid or limit salted peanuts and tomato juice. The salt may contribute to fluid retention and swollen tissues.

Limit carbonated drinks if the gases in them cause you abdominal distress.

Wear loose-fitting clothing. Also, wear roomy shoes or sneakers and take them off in flight.

Get up and walk around the cabin every 45 to 60 minutes on long flights.

Swallow, yawn or chew gum to equalize ear pressure.

To avoid motion sickness:

Sit on an aisle seat near the center of the plane, not over a wing where you're more likely to feel engine vibration.

Avoid heavy, spicy or salty meals before or during flight.

To combat stress, relax your shoulders, close your mouth and inhale as slowly and deeply as you can to the count of eight. Repeat this deep-breathing exercise five times.

Or close your eyes and imagine yourself in a peaceful surrounding.

Or, if it works for you, read a novel.