A woman was killed yesterday in a fire that gutted a fourth floor apartment of the Roosevelt residence for senior citizens at 2101 16th St. NW, the D.C. Fire Department reported.

The fire marshal's office tentatively identified the victims as Esther Weisz, 76, of the 16th Street address. The cause of the fire was listed as smoking in bed. Damage to the apartment was put to about $10,000.

No other injuries resulted from the blaze, which was reported at 5:18 p.m., and no evacuation of the building was necessary, fire officials said.

One resident interviewed last night said he was in the dining room at the time and was unaware of the fire. A woman on the eighth floor said she remained inside her apartment with the door closed.

At least one resident said she first learned of the death from a news report on television.

The department said about 50 firemen were involved in fighting the blaze.

Earlier yesterday, four persons received hospital treatment as a result of two other fires - one in a House of Representatives office building, the other in a two-story house on Jefferson Street NW, D.C. fire officials reported.

They said one of the fires was reported about 8:50 a.m. in House Office Building Annex No. 2, at 2d and D Streets SW, which formerly housed FBI records. The building now is used for hearing rooms.

The Fire Department said the blaze broke out in a storage room on the first floor and caused about $500 damage. The cause was unknown.

Three Capitol Police officers who sought to extinguish the fire were treated for smoke inhalation at Providence Hospital. All were released.They were listed as Edward Humphries, 26, Dale Wold, 28, and Ralph Giardino, 42.

At about 4:30 a.m., the Fire Department said, fire gutted both floors of a house at 1106 Jefferson St. NW, causing about $25,000 damage. Officials said the fire was ignited by a portable electric heater on the first floor and spread upward.

They said an occupant of the house, identified as Joel Beavers, 39, jumped from a second floor window. He was treated for a back injury at the Washington Hospital Center and later transferred to the Veterans Administration Hospital, officials said.