Milo T. Hoots Sr., a retired Falls Church real estate agent who was active for many years in Northern Virginia Republican politics, died Wednesday of kidney failure in Winston-Salem, N.C. He was 68.

Since January, 1976, he had ben living in his native town, Yadkinville, N.C.

Mr. Hoots came to Northern Virginia in 1937 as a salesman for the R.J. Reynolds Tobacco Co. for the Washington area. From 1949 until he retired last year, he had headed his own real estate agency.

He was a member of the 10th District Republican committee for about 10 years and was an active worker in many local Republican campaigns.

In 1959, he was the party's condidate for Fairfax County sheriff, but was defeated by Democrat John E. Taylor.

Mr. Hoots was a founding member of the Boulevard Baptist Church in Falls Church and of the Baileys Crosroads Volunteer Fire Department. He also was an Elk and a Mason.

His first wife, Lydia Williams Hoots, died in 1974.

He married in 1975 to Dorothy Blackwood Copple, who survives him. Other survivors are two sons, Milo Jr., of Washington, and H. Frank, of Rockville; a daughter, Carolyn Johnson, of Memphis, Tenn.; eight brothers; one sister, and six grandchildren.