Imogene E. Willis, a church worker active in numerous charitable groups, died Friday of cancer. She was 59.

Born in Martinsburg, W. Va., Mrs. Willis was a graduate of Storer College in Harpers Ferry, W.Va., where she majored in music.She continued her formal musical training at the Modern School of Music here.

After college, she and her family, moved to Scottdale, Pa., where she lived until her marriage to James R. Willis in 1944.

Mrs. Willis and her husband came here soon after he was discharged from military service. She became a member of the Florida Avenue Baptist Church and was a Sunday school teacher and den mother for the church Cub Scout troop for 15 years. She was also an organist and active in several other church activities.

Mrs. Willis was a member of the Emma C. Clements Court No. 2, Order of Calanthe, and an annual campaigner for the Heart fund, the Muscular Dystrophy Foundation, the Cancer Fund and other charities.

In addition to her husband, she is survived by two sons, Raymond E. and James S. both of Washington; two sisters, Nillie R. Hobson and Theola Fay Holley, both of Scottdale; two brothers, Bernhard Holley of Pittsburgh and Charles W. Holley of Chicago; four nieces, a nephew and a grandchild.