Paul Thomas Mavrikes, 51, and his wife, Anne K. Mavrikes, 50, of Lanham, was killed Sunday in a two-car collision in Georgetown, Del.

They were returning home from Ocean City Md., when the crash occurred. Two other persons from Delaware who were in the other car also died.

Mr. Mavrikes was president and co-owner with three brothers of Midway Florists in the Prince George's Plaza Shopping Center. His wife also worked at the flower shop.

He was a past president of the Prince George's Plaza Lions Club and of the New Carrollton Boys Club, Mrs. Mavrikes was active in the Ladies Auxiliary of the Boy's Club.

Born in New York City, Mr. Mavrikes served in the Pacific as an aerial gunner with the Army Air Corps in World War II. He later became a pilot and at one time owned and flew his own airplane here. He belonged to the Aircraft Owners and Pilots Association.

He was in the florist business in New York City until coming here in 1960, when he established Midway Florists with his brothers.

He also had been associated with the family investment firm, Lesvos Homes, Inc., in New York City since 1951, and had been named its president last year.

He was a member of the Prince George's Country Club. Both he and his wife were members of St. Sophia Greek Orthodox Cathedral in Washington.

Mrs. Mavrikes was born in Hartford, Conn., and was a graduate of the University of Connecticut. She had formerly worked with the Connecticut State Department of Education.

She was a member of Ahepta, a Hellenic organization.

They are survived by a son, George P., of the home in Lanham; a daughter, Mrs. Kalle Bannister, of Lindwood, N.J., and a grandchild.

In addition, Mrs. Mavrikes is survived by his mother, Calliope Mavrikes, of Lanham, and three brothers, Nicholas T., of Lanham, George T., of Landover Hills architecture at Auburn University in 1930.

Between her , and Theodore T., of Glenn Dale.