Carolyn Keane, 57, a associate of closer Look, a counseling program for handicapped children and their families, died of cancer Thursday at Sibley Memorial Hospital.

Through the federally funded Closer Look project, she specialized in counseling families with more than one handicapped individual. She also worked to help open the job market and combat discrimination in employment and housing for handicapped young adults.

Born in Macon, Ga., Mrs. Keane

She first came to Washington in 1941, as an intern with the National Institute of Public Affairs and was assistant to the budget director of the Federal Works Agency.

Mrs. Keane was the wife of Mark E. Keane, executive director of the International City Management Association.

From 1958 to 1962, they lived in Oak Park, III, where he was city manager. They then spent four years in Tucson, Ariz., where he also was city manager, returning to Washington in 1966.

In addition to her husband, she is survived by seven children, Mark Jr., Peter, Brian and Barry, all of the home, Daniel, of Arlington, Dennis, of San Diego, Calif., and Mary, a student at Tufts University.

The family suggests that expressions of sympathy may be in the form of contributions to the Carolyn Keane Endowment Fund at the International City Management Association.