Edward S. Loder, 81, a retired engineer and fiscal specialist, died Tuesday at Sibley Memorial Hospital after a stroke.

A resident of Chevy Chase since retiring in 1960, he had spent much of his earlier years in Brazil.

From 1945 to 1960, he was business manager for the American component of the Cooperative Brazil - U. S. Health Development Service.

Established under the Institute of Inter-American Affairs, it became part of the Point Four program, established in 1950.That was a predecessor of the Agency for International Development.

Mr. Loder worked in the interior of Brazil, helping in the development of clinics, health centers and sanitary water systems.

Born in Palo Alto, Calif., he earned a degree in engineering from Stanford University. He first went to Brazil in 1929 as a fiscal engineer for a subsidiary of the Electric Bond and Share Co. of New York.

After nine years there, Mr. Loder moved to Washington. During World War II, he was a civilian engineer with the Navy's Bureau of Yards and Docks here. He received the Meritorious Civilian Service award.

Mr. Loder, who had served in the U. S. Army in World War I, had been associated with real estate since moving here permanently in 1960.

He is survived by his wife, Olivia Pinto Monteiro Loder, of the home; a daughter, MaRia Luisa Rogers, of Gaithersburg; a brother, James, of Menlo Park, Calif.; two sisters, Altha Sears and Mary Binns, both of Pacific Grove, Calif., and one grandchild.

The family suggests that expressions of sympathy may be in the form of contributions to Stanford University.