Henry Francis Grady Jr., 54, a former Washington governmental affairs representatives first with the Bank of America, then with Bankers Trust Company of New York and finally with Wells Fargo Bank in San Francisco, died Monday in his home in San Francisco after a heart attack.

Mr. Grady, a native of Berkeley, Calif., graduated from Wesern High School in Washington. He attended Allegheny College in Meadville, Pa., and also the University of California in Berkeley.

In 1950, he joined the Bank of America. In addition to being its Washington representative, he was assistant vice president in international banking administration. After eight years, he was named deputy director of the C.S. Development Loan Fund.

Two years later he joined Bankers Trust Company of New York as its Washington representative and after three years left to become vice president and treasurer of Porter International Company.

Mr. Grady left Washington in 1966, to become vice president of Wells Fargo Bank in san Francisco. He was also its national governmental affairs representative at the time of his death.

He was a member of the Metropolitan Club in Washington and was on the board of directors of the Bankers Political Action Committee.

Survivors include his wife, Marijo, and a son, Henry Francis III, both of the home in San Francisco; three daughters, Meeghan, of the home, Lucretia G. Mangum, of San Francisco and Wendy Robin, of San Francisco; two brothers, Reginald delValle, of Hillsborough, Calif., and John Weston, of San Fernando Valley, Calif., and a sister, Mrs. John Paton Davies, of Paris, France.