One hundred D.C. police officers made simultaneous raids on 22 locations Thursday, arresting 23 persons and seizing $145,000 in cash in what police called the culmination of a three-month gambling investigation.

Armed with arrest and search warrants that police said were issued on the basis of surveillance and observation, the raids, led by the second district vice unit, were made at 2 p.m. and required the breaking down of several doors. No injuries were reported.

Police said the arrests followed as investigation into what they described as a lottery and sports betting operation that may have handled bets at the rate of about $10 million a year.

According to police, Robert Hamilton Ellis, 65, who identified himself as a service station owner, was arrested at his home at 811 20th St. NE. Police said they seized $107,000 in the course of his arrest. They said he was charged with operating a lottery.

Alfred Calvagna, 69, listed at 6345 31st Pl. NW, was arrested at his home, and $25,000 was seized there, police said. They said he was a charged bookmaking, maintaining a gramblind establishment and operating a lottery.

All the others arrested were charged with operating a lottery, police said.

According to police, 70 telephones and 12 firearms, also were seized during the raids.