Dr. Samuel B. Ginsberg, 86, a dentist who had practiced for more than 50 years in Washington and Adelphi, died Friday at his home in Silver Spring.

He retired in 1965 after maintaining offices for 10 years in Adelphi. Before that, he had practiced in Washington, first with the Veterans Administration, and later had private offices in the Medical Science Building and the Burlington Hotel.

Born in Baltimore, Dr. Ginsberg graduated from George Washington University Dental School in 1914.

In World War I, he was a captain in the Army Dental Corps. Attached to the 328th Infantry of the 82d Division, he participated in a number of major campaigns and held the French Croix de Guerre.

Dr. Ginsberg was an active member and officer of the Beltsville Garden Club. He was a 32d degree Mason, a Shriner and a member of the Elks. He belonged to the D.C. Dental Society.

He is survived by his wife, Sophie, of the home: two daughters, Kaye Ehrlich and Mirima Rothchild, of Silver Spring; a son, Dr. David Ginsberg of Philadelphia; a brother, Alex and a sister, Bessie Gorfine, both of Baltimore; two other sisters, Rose Miller, of Washington, and Freda Schimmel, of York, Pa.; eight grandchildren, and a great-grandchild.

The family suggests that expressions of sympathy may be in the form of contributions to the Ethel Fisher Home Care Fund of the George Washington University Health Plan.