Louise W. Menikheim, 69, who worked for Woodward & Lothrop for 24 years, died Thursday at Suburban Hospital in Bethesda after an apparent heart attack.

Mrs. Menikheim retired in 1973 from the Chevy Chase store where she had been head of stock in the girls' department.

A past grand regent of the Catholic Daughters of America, she had been active in the Third Order of St. Francis, Villa Cortona. She had been a member of the parish of Our Lady of Lourdes Catholic Church in Bethesda. She was also a member of the American Association of Retired Persons.

Mrs. Menikheim was born in Baltimore and moved to Bethesda at an early age. She earned a bachelor's degree in English at George Washington University.

Mrs. Menikheim is survived by three daughters, Rosemary M. Olmert, of the home in Bethesda, Sister Marie Joanne, O.S.F., of Spartanberg, S.C., and Phyllis M. Drake, of Santee, Calif.; a brother, James P. Wenchel II, of Washington; eight granchildren, and one great-grandchildren.

The family suggests that expressions of sympathy may be in the form of contributions to the Coworkers of Mother Teresa, in care of Monsignor J. Richard Feiten, Box 6546, Rochester, Minn., 55901.