Dr. K. Kenneth Hisaoka, 53, a scientist and administrator with the National Institute of Health since 1963, died of cancer Friday at the NIH Clinical Centre.

Dr.Hisoaka joined NIH as a grants associate, later became a program chief in the National Institute of Dental Research, and had been an associate director of the National Institute of neurological Communicative Disorders and Stroke since 1977.

Born in British Columbia, he earned a bachelors degree at the University of Alberta, a master's degree at the University of Western Ontario, and a doctrate at Rutgers University.

Before moving to Washington in 1963, he taught biology at Loyola University in Chicago.

Dr. Hisaoka was a judo enthusiast, and held the rank of godan, or fifth degree black belt. He was a member of the U.S. Judo Federation and had been president of the Montgomery Couty Judo Club.

He was a member of the North Bethesda United Methodist Church.

His first wife, the former Renko Kuzuhara, died in 1971.

He is survived by his second wife , Frances, a son, Robert, a daughter, Joan, two stepdaughters, Robin and Harolyn, and a stepson, Micheal, all of the home in Potomac.

The family suggests that expressions of sympathy be in the form of contributions to the American Cancer Society or the Clinical Centre at NIH.