Anthony F. Arpaia, 80, who served on the Interstate Commerce Commission from 1952 to 1960 and was its chairman in 1956, died of congestive heart failure Saturday in Bradenton, Fla. He had moved there a year ago after living in St. Petersburg for 10 years.

While serving with the ICC, Mr. Arpaia was a member of the U.S. National Commission to the Pan American Railway Congress in 1956 and 1957. He also presided at sessions of the International Standards Organization (on transportation) in Germany, The Hague and Moscow.

Mr. Arpaia was born in New Haven, Conn. A graduate of Yale Unversity and its law school, he practiced corporate and public utility law in New York, international law in Berlin, Germany, and corporate and tax law in New Haven.

During World War II, he was state director of the Connecticut Office of Price Administration. After he resigned from the ICC in 1960, he became international vice president of Railway Express Company in New York. He retired from the firm in 1965, then worked as a consultant until this year.

In 1961, Mr. Arpaia conducted a mass transit pilot study for the Senate Interstate and Foreign Commerce Committee that led to the Mass Transit Act of 1963.

He is survived by a daughter, Judith Sedgeman, of Bradenton; five brothers, Frank, of Bradenton, Nicholas, of St. Petersburg, William, of Chicago, and Charles and Tom, of New Haven; two sisters, Mary Cousins, of Woodbridge, Conn., and Jean Florio, of New Haven, and one grandchild.

The family suggests that expressions of sympathy may be in the form of contributions to the Youth Scholarship Fund of the Florida West Coast Symphony Orchestra in Sarasota, or to the Amity Club Youth Scholarship Fund in New Haven.