Edwin E. Brown, 75, an employe of the Southern Railway System for 42 years until his retirement in 1965, died of cancer Monday at Calvert Memonrial Hospital in Prince Frederick, Md.

Mr. Brown, a native of Washington, began working for Southern Railway in 1923 as a secretary to the company president. He was based in Alabama and South Carolina before returning to this area in 1950, where he worked as a train master for the Alexandria Washington division for a number of years.

At his retirement, Mr. Brown was a transportation assistant for the railroad.

Mr. brown then became active in retirement organizations. In the mid-1960s, he helped to organize and served as president pro tem of the American Association of Retired Persons in Alexandria; where he lived until moving to Lusby, Md., two years ago.

He had served as an usher at Trinity United Methodist Church in Lusby and was a member of the Tuesday Lunch Bunch, a church organization for retired people.

Mr. brown was a member of the Masons, Joppa Lodge No. 35 FAAM, and was active on the lodge's memorial committee.

Survivors include his wife of 44 years, the former Grace Lank, of the home in Lusby; two sons, David E., of Gaithersburg, and Thomas W., of Locust Grove, Va.; two sisters, Marian Mills, of Silver Spring, and Ruth Deaton, of Biscoe, N.C., and six grandchildren.

The family suggests that expressions of sympathy be in the form of contributions to The Solomons Rescue Squad, Solomons, Md.