Louise L. Lytzen, 23, who was killed early Friday in an automobile accident on the George Washington Memorial Parkway, was a lifelong resident of this area and an accountant with Unified Industries in Alexandria.

She was born in Washington and gre up in Chevy Chase. She attended elementary school at The Church of the Little Flower in Bethesda and later graduated from Walt Whitman High School.

Miss Lytzen worked as an accountant for Microbiological Associates in Bethesda before moving to Unified Industries. She also attended night classes at George Mason University. She recently had moved to McLean.

U.S. Park Police said Miss Lytzen was sitting in her parked car on the Washington Parkway in Virginia near the Cabin John Bridge. The driver of a second car stopped to see if she needed assistance and a third car struck the rear of Miss Lytzen's car. She was pronounced dead at the scene. Police said no one else was injured in the accident.

Miss Lytzen's survivors include her parents, Mr. and Mr. William W. Lytzen, of Chevy Chase, a brother, Kendall, also of Chevy Chase, and a grandmother, Mrs. G. W. Hyatt, of Bethesda.

The family suggests that expressions of sympathy be in the form of contributions to the Humane Society. CAPTION: Picture, LOUISE L. LYTZEN