Naomi Rose Bekenstein, 43, who was active in professional, service and cultural activities in this area, died of cancer Wednesday at her home in Vienna.

The wife of Dr. William L. Bekenstein, a Fairfax pediatrician, she was a past president of the Fairfax Medical Society's Women's Auxiliary and a past chairman of the American Medical Society's education and research foundation for the state of Virginia. At her death, she was treasurer of the auxiliary of the Medical Society of Virginia.

She also had served as crusade chairman of the Northern Virginia chapter of the American Cancer Society and headed the chapter's annual ball, which she founded three years ago.

Mrs. Bekenstein was a former president of the Temple Rodef Shalom Sisterhood in Falls Church and was active in the American Heart Association and the women's committee of the National Symphony.

She was born in Brooklyn, N.Y., and earned a bachelor's degree in business from West Virginia University.

Besides her husband, survivors include three children, Jane, Jonathan and David, all of the home in Vienna, and her parents, Rabbi and Mrs. Morris M. Rose, and a brother, Rabbi Herbert H. Rose, all of New York City.

The family suggests that expressions of sympathy be in the form of contributions to the Naomi R. Bekenstein Memorial Fund, Temple Rodef Shalom. CAPTION: Picture, NAOMI R. BEKENSTEIN