Shirley Henry Minus, 38, who was killed in an auto accident on Randolph Road in the Colesville section of Silver Spring on Saturday, was director of student loans at American University.

According to police, the vehicle Mrs. Minus was driving had crossed the median and collided with another auto. Mrs. Minus was thrown from her car and was pronounced dead at Holy Cross Hospital in Silver Spring. The driver of the other car was treated for a broken leg.

Mrs. Minus came to Washington in 1965 and worked as a systems analyst for IBM before joining the treasurer's office at American University in 1973. She was named director of student loans earlier this summer.

She was a 1978 graduate of American University's law school and received the outstanding alumnus of the year award from the law school that year.

She had been a Cub Scout den mother and Brownie assistant in Silver Spring for the past three years. She also was a member of the Colesville Methodist Church where she served as an education assistant.

Mrs. Minus was born in Salisbury, N.C., and earned a bachelor's degree in physics at Fisk University in Nashville, Tenn.

She lived in Cleveland and in New York City before coming to Washington.

Survivors include her husband, Dr. Harold R. Minus Jr., a son, Harold R. III, and a daughter, Elaine M., all of the home in Silver Spring; her father, Robert A. Henry Sr., of Clover, S.C.; four sisters, Janie E. Greene, Joann Worthy, Betty Jean White, and Marilyn Henry, and a brother, Robert A. Henry Jr., all of Cleveland. CAPTION: Picture, SHIRLEY HENRY MINUS