Elizabeth H. Hopkins, 80, an area practical nurse for 15 years, died Saturday at Loudoun Memorial Hospital in Leesburg.

From 1949 to 1953 Mrs. Hopkins was on the nursing staff of Chestnut Lodge in Rockville. She then spent six years as a nurse with the National Institutes of Health. She worked at Northern Virginia Doctors Hospital in Arlington from 1960 to 1964; then joined the staff at Loudoun Memorial Hospital, where she worked until retiring in 1973.

She was a member of the Black Horse Chapter of the United Daughters of the Confederacy in Warrenton, Montgomery Chapter No. 93 of the Order of the Eastern Star in Rockville, and had been musical director of Job's Daughters in Rockville in the early 1930s. She attended the Christian Science Church in Warrenton.

Mrs. Hopkins was a native of Charleston, W.Va., and studied piano at the Kanawha Valley Conservatory of Music there. She earned her practical nursing degree at Georgetown University in 1960.

Survivors include two sons, Frederick W. Berens Jr., of Bethesda, and Robert Hopkins, of Florida; three daughters, Betty Jane Petersen, of Bethesda, Carol J. Countrymen, of Leesburg, and Rosemary H. Jones, of Ashland, Va., eight grandchildren, and one great-grandchild.

The family suggests that expressions of sympathy be in the form of contributions to the Psychiatric Building Fund of Loudoun Memorial Hospital, 70 West Cornwall St., Leesburg, 22075.