Elisabeth Harry Derrick, 73, a third-generation Washingtonian active in club and church work here, died of cancer Friday at her home in Washington.

She had lived all her life in the northwest Tenleytown section of the city.

Mrs. Derrick was a graduate of McKinley Tech High School and the old Wilson Normal School. In the 1920s, she taught at John Eaton Elementary School and then at Mrs. Cook's School, a private education facility.

She married her childhood sweetheart, Franklin L. Derrick, now retired, who owned and operated a decorating business. They celebrated their 50th wedding anniversary last June.

Mrs. Derrick was a charter member of the Town and Country Garden Club and belonged to the Inner Wheel of Bethesda.

She was a member of Eldbrooke United Methodist Church, where she had been a Sunday school teacher and superintendent, a Circle leader and a member of United Methodist Women and the administrative board.

In addition to her husband, of Washington, she is survived by four children, Barbara D. Tate of Alexandria, F. Lee Derrick Jr. of Clarion, Pa., Priscilla D. Ricker of Smyrna, Del., and C. Richard Derrick of Galesville, Md.; three sisters, Ida Wood of Annapolis, and Sabra Sullivan and Rebecca Parker, both of Washington; a brother, Lawrence W. Harry of Washington, and 14 grandchildren.