John E. Lewis, 60, president of the National Small Business Association, died Wednesday in a hospital in Richmond of injuries suffered in a traffic accident two days earlier.

Virginia State Police said Mr. Lewis was struck by a car while he was crossing a street to catch a bus near Fredericksburg. Police said no charges were brought against the driver of the car.

Mr. Lewis came to Washington in 1965 to join the National Small Business Association staff. He became the association's executive vice president four years later and president in 1977. He also was executive director of the Small Business Legislative Council.

He participated in the White House Conference on Small Business held last month.

He was also a member of the board of trustees of the National Patent Council and belonged to the National Association Executives Club. He also was a member of the American and Washington societies of association executives.

Mr. Lewis was a native of Clarksville, Tenn., and a graduate of the University of Notre Dame. He earned a law degree at Vanderbilt University. He worked for the Anderson Company in Gary, Ind., before coming to this area. He had lived in Annandale until moving to Fredericksburg last July.

Survivors include his wife, Delores, and a daughter, Karin, both of Fredericksburg; a son, Brian, of Pasadena, Calif., and one grandchild.