Dr. Herbert Vincent McKnight, 60, a Washington physician who also taught biochemistry at the Howard University School of Medicine from 1953 to 1963 died Tuesday at Washington Hospital Center. He had a heart ailment.

An internist, Dr. McKnight had maintained a private practice here from about 1950 until his death.

Besides teaching at Howard University for 10 years, he had served as medical director for the National Medical Association Foundation here. In this capacity, he organized outpatient clinical services at the Shaw Community Medical Center.

During the 1960s and 1970s, Dr. McKnight served at various times as a medical officer for the U.S. Food and Drug Administration, for the D.C. Health Department and the D.C. Police and Fire Clinic.

Dr. McKnight, a Washington resident, was born in Charleston, S.C. and grew up in New York City. He earned a bachelor's degree in chemistry from St. John's University in Collegeville, Minn., where he studied under a scholarship. In 1945, he earned a medicine degree from the Howard University College of Medicine and then served as a resident physician at the old Freedmen's Hospital here.

Before starting his Washington practice, he spent two years at the Sioux Indian Sanitarium in Rapid City, S.D., where he specialized in treating tuberculosis.

Surviros include his wife of 35 years, the former Alma Mitchell, three daughers, Jo-Anne, Alice, and Leslie Yates, and five sons, Herbert V. Jr., Julian, Albert, Thomas and Timothy, all of Washington; another son, Dr. John E. of Pittsburgh; five sisters, Loleta Doar, Marietta Hammack, Elizabeth Newsome, Ernestine Siverls and Margaret Blake, all of New York, and a granddaughter.