Anne Martin Seal, 51, a descendant of John and Priscilla Alden and Myles Standish, died Sunday at her home in Chevy Chase of cancer.

Mrs. Seal had resided in the Washington area since 1946 after dividing her girlhood between Massachusetts and Washington. She was a 1947 graduate of Bethesda-Chevy Chase High School.

At the age of 41, when her four sons had groun up, Mrs. Seal entered college for the first time, attending Montgomery College and later American University.

After doing volunteer work at the D.C. Corrections Center at Lorton, Mrs. Seal studied the administration of justice. At 45, she graduated from American with a bachelor's in administration of justice.

She then served as a correctional officer for the District and later as a parole officer in Maryland.

She was the daughter of the late Dr. Robert F. Martin, who once headed the Bureau of Foreign and Domestic Commerce in the Franklin D. Roosevelt administration and who held similar posts in the Hoover, Eisenhower, and Kennedy administrations.

When Mrs. Seal's maternal grandfather, Elijah Alden, married her maternal grandmother, Minnie Howard Snow, it was at least the second time the Alden and Standish famlies had been united. A daughter of John and Priscilla Alden had married a son of Myles Standish to bring together in one family the principal subjects of Henry Wadsworth Longfellow's "Courtship of Myles Standish."

A resident of Chevy Chase for almost 20 years, Mrs. Seal had been honored for her volunteer work with the Cerebral Palsy Association of Montgomery County.

She was a longtime member of the Chevy Chase Women's Club and was a member of the Daughters of the American Revolution. She briefly served as president of the Chevy Chase chapter of DAR.

Mrs. Seal is survived by her husband, Frank W. Seal of Chevy Chase; three sons, Robert Edward of Portland, Maine; Howard Dudley of Anne Arundel County and James Daniel of Washington; two brother, Robert L. Martin of Farmington, Maine, and John S. Martin of Nevada; and seven grandchilden. Her fourth son, Frank W. Seal Jr., died in 1976.