Dr. Margaret M. Kenrick, 59, chairman of the Department of Physical Medicine & Rehabilitation at Georgetown University's medical school since 1969, died of cancer Saturday at her home in Fort Sumner Hills, Md.

She was a delegate from the American Congress of Rehabilitation Medicine to the President's Commitee on Hiring the Handicapped in the mid-1960s. She also was a delegate to the second White House Conference on Aging, held in 1971.

Dr. Kenrick joined the faculty at Georgetown in 1956. Since that time she had worked to make life easier for the handicapped at both Georgetown and the community at large.

A spokesman at the Georgetown Medical Center said that it was not until after Dr. Kenrick joined the university that carpeting -- specially suited for wheel chairs -- and access ramps around the hospital and campus where installed. Dr. Kenrick also had been a consultant to groups working for greater access of the handicapped to the Metro system.

She served on the board of directors of the National Paraplegic Foundation from 1965 to 1967 and on the board of the D.C. chapter of the United Cerebral Palsy organization since 1959.

Dr. Kenrick was a consultant on physical medicine and rehabilitation to a number of area institutions over the years, including the Veterans Administration Hospital, the Washington Hospital Center, and the National Institutes of Health.

She was chairman of the Southern Medical Association from 1973 to 1974. and chairman of the D.C. Medical Society's Physical Medicine and Rehabilitation Section since 1956. She received the D.C. Medical Society's Community Service Award in 1967.

Dr. Kenrick was a native of New York City and a 1941 graduate of Ithaca College, Ithaca, N.Y. She graduated from the New York Medical College in New York City in 1952.

She interned at Queens General Hospital in New York City and later was chief resident in physical medicine and rehabilitation at the Georgia Warm Springs Foundation in Warm Springs, Ga. While at Warm Springs she worked with polio patients.

Since joining the faculty at Georgetown University's medical school she had been active on a number of committees. She served on the admissions committee of the medical school from 1971 to 1976, and was chairman of the committee on faculty appointments in 1978.

In addition to being chairman of her department at the medical school, she also was a full professor, and also had been director of the Department of Physical Medicine and Rehabilitation at the Georgetown University Hospital since 1961.

Dr. Kenrick's survivors include two sisters; Kathleen Annarella of Fort Sumner Hills, and Mary Zinsley of Long Island City, N.Y., and two brothers, John Kenrick of Long Beach, N.Y., and Dr. Joseph Kenrick of Bethesda.

The family suggests that expressions of sympathy be in the form of contributions to the Dr. Margaret M. Kenrick Memorial Lectureship at the Georgetown University School of Medicine, c/o the Department of Physical Medicine & Rehabilitation.