Anthony J. Perruso, 62, former owner of restaurants and a delicatessen in the Washington area and retired taxicab driver, died of cancer Wednesday at Greater Laurel Beltsville Hospital in Laurel.

Mr. Perruso was born in Washington and graduated from Eastern High School in 1935. He played the banjo and he and his brothers, Vito and James, formed the Perruso Brothers Band, which played restaurant and similar engagements in the Washington area in the late 1930s and early 1940s.

In the 1940s, the brothers opened Perruso's Restaurant on North Capitol Street. They later moved to Georgia Avenue NW. That business was sold about 1949. Mr. Perruso then drove a truck for the old Holmes Bakery and for the Thompson Dairy Co.

From 1957 to 1962, he operated Perruso's Delicatessen on University Boulevard in Adelphi. Then he opened Perruso's Restaurant in Laurel and ran that busines until 1965, when he sold it. Mr. Perruso drove a taxi for the Blue Bird Cab Co. in Hyattsville until his retirement in 1977.

Survivors include his wife of 35 years, Nancy Harper Perruso, of Laurel, where the family lives; five daughters, Carol, of San Diego, Calif., Gail, of Washington, and Toni, Nancy and Lorraine, all of Laurel; a son, James, of Colorado Springs, Colo.; his mother, Aida, of Washington; four sisters, Edith, Delores and Rose Perruso, all of Washington, and Philomena Healy, of Port St. Lucie, Fla., and a brother, Vito, of Virginia Beach. James Perruso died in 1959.

The family suggests that expressions of sympathy be in the form of contributions to the Greater Laurel Beltsville Hospital, Van Dusen Road, Laurel, Md., in care of Susan Turner.