William Frederick Blocher, 68, the president and principal owner of Blocher Reprographics Inc., a firm which specializes in printing blueprints, architectural drawings and similar material, died Sept. 22 at Holy Cross Hospital in Silver Spring. He had a respiratory ailment.

Mr. Blocher was born on a farm near Wyalusing, Pa. and grew up there. He earned a degree in accounting at Rider College in Trenton, N.J., and moved to the Washington area in 1930.

For the next 14 years, he engaged in baking. He also earned a law degree at National University. In 1944, he joined the Goetz Co., which does reprographics -- the printing of such things as blueprints. He was the comptroller and vice president.

In 1956, he formed his own company, the Blocher Blueprint Supply co. In 1961, he merged that firm with five others to form the Allied Blueprint co., which later became Blocher Reporgraphics Inc.

Mr. Blocher also had other business interests. They included Engineering Reproductions Inc., which he helped found in Buena Park, Calif. in 1957, and the BMB Management Corp. which he helped found in 1958 and which leases equipment to the printing industry. Engineering Reproductions Inc. became a division of Blocher Reprographics in 1977.

Mr. Blocher was a former director and president of the International Association of Blueprint and Allied Industries.

He was a resident of Bethesda for many years and was a past president of the Pilgrim Lutheran Church there. From 1972 to 1979, he lived in Newport Beach, Calif., and was a director of the Buena Park Boys Club and president of the Buena Park Rotary Club. He returned to the Washington area last year and lived in Gaithersburg at the time of his death.

Mr. Blocher's survivors include his wife, Dorothea, of Gaithersburg; four sons, William F. Jr., of Broad Run, Va., Ronald, of Potomac, Robert, of Washington, and Roy, of Darnestown, md.; one daughter, Alice Knudsen of Piedmont, Calif., and seven grandchildren.