Two elderly District women were killed and two other persons were seriously injured yesterday in a traffic wreck in Laytonsville in northeastern Montgomery County.

Montgomery County police said that a car containing three women and one man -- all from the District and in their late 70s and early 80s -- was traveling north on Brink Road about 1 p.m. when it collided with a pick-up truck traveling on Maryland Rte. 108 and driven by a 40-year-old Frederick, Md., man.

Although investigators said that it was not a high speed collision, one woman died at the scene and a second woman died after being flown by a state police helicopter to a shock-trauma center in Baltimore, police said. Dispatchers said the remaining victims were sent to Montgomery General and Suburban hospitals.

The dead were identified as Minerva May, 80, who died at the scene, and Eleanor Loomis, 80, who died about 4 p.m. at the shock-trauma unit.

The injured were identified as William S. Rumbough, 87, the driver, and Armine Hammond, 80.

Police said all four the car's occupants were residents of 3133 Connecticut Ave. NW.

The driver of the pickup truck was identified as Larry Sigler of Union Bridge, Md.

An investigation into the cause of the accident was continuing late yesterday, police said. But one investigator said that there was a stop sign on Brink Road at the intersection where the crash occurred, and that the driver of the pick-up truck was not at fault in not stopping.