Mary Graeff Caplan, 39, a retired financial analyst at International Brotherhood of Teamsters headquarters here and a lifelong Washington-area resident, died of cerebral anoxia Saturday at Suburban Hospital in Bethesda.

Mrs. Caplan was born in Washington and graduated from Walter Johnson High School in Bethesda. She later became a chartered financial analyst.

Before joining the Teamsters investment department in 1976, she worked for a number of years as a financial analyst for Thomson McKinnon Securities and United Services Life Insurance Co., both of Washington. She retired about two years ago to devote more time to her family.

Mrs. Caplan, who lived in Bethesda, belonged to the New York Avenue Presbyterian Church here, where she had taught sewing classes for several years. Also a member of the Washington Society of Investment Analysts, she was the group's education chairman at the time of her death.

Survivors include her husband, Henry, and a son, Michael, both of Bethesda; her parents, Allan H. Sr. and Elizabeth Graeff, of Kensington; and two brothers, Edward, of Columbia, Md., and Allan Jr., of Port-au-Prince, Haiti.

The family suggests that expressions of sympathy be in the form of contributions to Suburban Hospital, or to a charity of one's choice.