Lois Oliver Neuhaus, 81, a retired secretary in the Bureau of Entomology at the Agriculture Department, died of cancer Tuesday at her home in Silver Spring. She had lived in the Washington area since 1901.

Mrs. Neuhaus was born in Baltimore. She was a graduate of the old Business High School in Washington and worked for the U.S. Shipping Board during World War I.

She left federal government service after the war, then returned during World War II to work for the Civil Service Commission. She transferred to the Agriculture Department in 1949 and remained there until retiring in 1962.

Mrs. Neuhaus was a member of Lebanon Chapter No. 25 of the Eastern Star, the Woodridge Book Club, the Takoma Park Woman's Club and the Takoma Park Senior Citizens club. She had been active in the Episcopal Church of Our Saviour in White Oak, Md.

She is survived by her husband of 60 years, Paul I. Neuhaus of Silver Spring; a daughter, Lois N. Webb of Port Republic, Md.; a son, Paul I. Jr., of Olney; a brother, Sidney M. Oliver of Rossmoor Leisure World in Silver Spring; a sister, Grace Stephens of Severna Park, Md., three grandchildren, three stepgrandchildren and two great-grandchildren. m