Ora Lee McDonald, 69, a former chairman of the board of the Washington Heart Association and a volunteer in several other service organizations, died of kidney failure Sunday at the Wisconsin Avenue Nursing Home.

Mrs. McDonald was born in Slayden, Tenn., and grew up there and in Clarksville, Tenn. She and her first husband, Daniel Jones, lived in Detroit. Mr. Jones died in 1941 and the future Mrs. McDonald was a legal secretary in Detroit until 1947, when she moved to Washington.

She was a legal secretary here until 1953, when she married Harry McDonald, a former chairman of the Securities and Exchange Commission.

In addition to her work with the Washington Heart Association, Mrs. McDonald was a member of the women's auxiliary of the Salvation Army and a volunteer at the Florence Crittenton Home. She donated a heart machine to the George Washington University Hospital and helped to fund the Music Auditorium at American University.

Mrs. McDonald, whose second husband died in 1964, maintained her own residence in Washington until last April, when she moved to the Wisconsin Avenue Nursing Home. She was a member of the Metropolitan Memorial United Methodist Church.

Survivors include a son, Richard Russell Jones of Victorville, Calif., three sisters, Ruby Lakin of Port Charlotte, Fla., Catherine Brown Drinkard of Birmingham, Mich., Martha Wilson Foersterling of Hinsdale, Ill., and two grandchildren.

The family suggests that expressions of sympathy be made in the form of contributions to the Washington Heart Association, 2233 Wisconsin Ave. NW, Washington, D.C. 20007