Leola T. Deming, 78, who retired from the Federal Trade Commission in 1964 after 38 years of federal service, died Monday at Sibley Memorial Hospital following a stroke. She lived in Washington.

Miss Deming was born in Onaway, Mich., and moved to Washington with her family in 1907. She graduated from the old Eastern High School.

About 1926, she went to work for the alcohol and tobacco tax section of he old Bureau of Internal Revenue. She became involved in statistical work and remained in this field for the rest of her career. In World War II, she transferred to the Federal Maritime Commission and after the war went to the FTC.

There she worked in the bureau of economics, compiling information to support litigation and complaints filed by the commission. She received a special commendation for this work.

Her marriage to Raymond Miller ended in divorce in 1937 and Miss Deming resumed her maiden name.

Survivors include two stepchildren, Raymond V. Miller of Stafford, Va., and Marilyn M. Lansdale of Napa, Calif., and a brother, Arthur R. Deming of Washington.

The family suggests that expressions of sympathy be in the form of contributions to Metropolitan Memorial United Methodist Church, Nebraska and New Mexico avenues NW, Washington, 20016.