Jose R. Chiriboga, 69, a former foreign minister of Ecuador and the ambassador of Ecuador to the United States from 1952 to 1960, died Wednesday at Sibley Memorial Hospital. He had arteriosclerosis.

For the last 20 years, Mr. Chiriboga, a resident of Bethesda, had been an official of the Inter-American Development Bank. He was a former deputy general counsel of the bank and at the time of his death was an adviser and acting chief of the office of the bank's president. As deputy general counsel, he was responsible for supervising hundreds of loans totaling more than $9 billion to the bank's borrowers.

A native of Quito, Ecuador, Mr. Chiriboga took a law degree at the Central University of Ecuador. He bagan his government career in 1939 and held a number of appointed and elected posts, including three terms as mayor of Quito. He was appointed ambassador to the United States in 1952 and for the next four years also was Ecuador's ambassador to the Organization of American States. He was his country's foreign minister in 1960. He ran for the presidency of Ecuador in 1952 and in 1956.

He joined the legal staff of the Inter-American Development Bank in 1961.

His first marriage ended in divorce.

Survivors include his wife, Norma, from whom he was legally separated, of Potomac; two sons by his first marriage, Hernan and Enrique, both of Quito; a daughter by his second marriage, Dianna, of Rockville, and three grandchildren.