Frederick B. Tuttle, 72, a special assistant in the academic affairs division of the National Aeronautics and Space Administration, died May 15 at Yale-New Haven Hospital in New Haven, Conn., following a heart attack. He was stricken while attending a seminar at Yale University.

Dr. Tuttle, who lived in Washington, began his government career in aerospace education in 1946 with the old Civil Aeronautics Administration, now the Federal Aviation Administration. In 1963, he transferred to NASA and was appointed director of educational programs in its Office of Public Affairs. In the course of his career, he directed many academic courses and workshops in connection with the space program and developments in aerospace science.

Among his honors were the Frank G. Brewer Trophy for outstanding service to aerospace education, which he received in 1973, a citation from the Committee for the Celebration of the 50th Anniversary of Powered Flight, and the Crown Circle Award of the National Congress on Aerospace Education, which he received in 1979.

Dr. Tuttle was a member of numerous hereditary organizations, including the Society of Colonial Wars, the Baronial Order of the Magna Charta, the Descendants of Colonial Governors, the Descendants of Loyalists and Patriots of the American Revolution, the Order of the Crown of Charlemagne, the Sons of the American Revolution and the Descendants of the Colonial Clergy.

Dr. Tuttle, who was born in New Haven, earned bachelor's and doctoral degrees from Yale. In the 1930s, he was a teacher and then a principal in the public school system of New Haven, the superintendent of schools in Westerly, R.I., and the dean of graduate studies for the summer session of the State University of New York at Plattsburgh. During World War II, he served in the Marine Corps. He then moved to Washington to work for the government.

Dr. Tuttle was a member of the Cosmos Club and the Yale Club of Washington.

His first wife, Mary Emily Armstrong, died in 1972.

Survivors include his wife, the former Eleanor Brooke Perry, of Washington; four children by his first marriage, Margaret Emily Alta of Washington, Dr. Frederick B. Jr., of Los Angeles, James A., of Germantown, Md., and Allen C., of Sterling, Va.; one brother, Howard G., of Branford, Conn., and three grandchildren.